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Table 4 Diagnostic performances of Cyscope® FM with regard to clinical status

From: Comparison of the fluorescence microscopy Cyscope® with light microscopy for malaria diagnosis in a small and active surveillance in Cameroon

Parameters All (n = 441) Febrile (n = 56) Afebrile (n = 385) P value
Value 95% CI Value 95% CI Value 95% CI
Se (%) 84.00 74.08–90.60 57.14 25.04–84.18 86.76 76.71–92.87 0.74
Sp (%) 69.95 65.07–74.42 65.3 51.32–77.08 70.66 65.42–75.40 0.92
PPV (%) 63.58 56.19–70.38 19.05 7.67–40.0 38.81 31.44–46.75 0.3
NPV (%) 95.55 88.31–94.72 91.43 77.62–97.04 96.13 92.83–97.96 1
PLR 2.8 1.65 NA 2.95 NA
NLR 0.23 NA NA NA NA
Accuracy (%) 89.36 83.34–90.21 10.08 51.2–75.85 79.27 68.89–77.67 0.63
Reliability (%) 53.95 22.45 57.43
Kappa 0.45 -
  1. CI Confidence interval, FM Fluorescence microscopy, Se Sensitivity, Sp Specificity, PPV Positive predictive value, NPV Negative predictive value, PLR Positive likelihood ratio, NLR Negative likelihood ratio, NA Not applicable. Pearson’s chi-square test was used to make comparisons. Significance was set at p value < 0.05