In vitro effects of febrifugine on Schistosoma mansoni adult worms

Table 2 Effect of febrifugine on the survival time of six paired Schistosoma mansoni adult worms within 14 days

Concentration of febrifugine (μg/ml)	Median survival days (range)		P value^b
Concentration of febrifugine (μg/ml)	Male	Female	P value^b
Experiment 1
0 (control)	ND	ND
0.05	12.0 (12–13)^a	12.0 (11–12)^a	0.18
0.1	11.0 (11)^a	9.0 (9–11)^a	0.00
0.2	10.5 (9–11)^a	8.5 (8–9)^a	0.00
0.5	8.0 (7–8)^a	7.0 (7–8)^a	0.09
Experiment 2
0 (control)	ND	ND	–
0.005	ND	ND	–
0.01	ND	ND	–
0.02	13.0 (13–14)^a	13.5 (13–14)^a	0.57

A log-rank test was used for the statistical analysis
ND death was not observed in any of the worms over the incubation period of 14 days
^aP value < 0.01, compared with the corresponding control group
^bCompared between male and female

ISSN: 1349-4147